Kerala Veterinary and Animal Sciences University

Research Highlights ,Recent Major Research Outcomes

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Kerala Veterinary and Animal Sciences University at its head-quarters in Pookode, houses an ICMR accredited COVID testing laboratory in the Dept of Veterinary Microbiology, CVAS, Pookode. The centre associates with district administration in management of COVID-19

An inactivated vaccine was developed against riemerellosis whichwas superior in terms of results obtained from the challenge study, antibody titre, cell mediated immune response and gene expression analysis than the subunit one. This vaccine has been recommended for use in field condition owing to its easiness to prepare and low cost.

In vitro and in vivo studies on effect of dietary incorporation of ayurvedic pharmaceutic gritham residues, which are rich in energy, protein and fibre as replacement for costly energy feeds like maize and protein supplements like soybean meal were carried out and it was proved that Brahmi gritham residue and Panchagavya Gritham residue could safely and economically be incorporated in the rations of Malabari kids, with beneficial effects on their growth performance.
Studies on dietary substitution of costly palm oil with cheaper rape seed oilshowed that substitution at different levels had no adverse on growth performance and economics of broilers.
An evaluation of different fractions of the semen ejaculate of Large White Yorkshire boars indicated that the initial 10 mL of sperm rich fraction showed better preservability at 150C than rest of the semen fractions.
Study of storage quality of liquid semen of Large White Yorkshire boar supplemented with cholesterol loaded cyclodextrin improved the quality of stored spermatozoa at 150C till 72 h. as indicated by improved progressive motility, sperm viability, functional membrane integrity and acrosome integrity after cryopreservation.
A novel recombinant 22.6 kDa tegument protein of Schistosoma spindale (rSs22.6) was expressed and characterized. The novel protein based ELISA had an sensitivity of 92.11 % and specificity of 100 %. The assay is field validated and can be commercialized as a diagnostic kit
Reported Haemaphysalis kutchensis and H.megalaimae for the first time in Kerala.
A study to detect the presence of antibiotic resistant bacteria from the enteric tract/ faecal samples of chicken showed that most of the isolates exhibited high degree of resistance to antibiotics such as enrofloxacin, ofloxacin, clindamycin, ciprofloxacin and methicillin. Among the isolates, one E. coli was resistant to all the antibiotics tested. Eight isolates including one K. pneumoniae and seven E. coli were found to be resistant to one or more than one carbapenems tested viz., imipenem, meropenem and ertapenem.
The presence of carbapenem resistant E. coli was confirmed in cattle and pigs.
A high prevalence of carbapenem resistance (31 per cent) was noted among the isolates of Esherichia coli, Kliebsiella pnuemoniae and Pseudomonas aeruginosa associated with skin and urogential tract infections in dogs
Seroprevalence of leptospirosis in goats in five districts of Kerala, Thrissur, Malappuram, Palakkad, Kozhikkode and Kannur, was studied by microscopic agglutination test and it was found to be 10.80 per cent. Serogroup Pomona was the most prevalent one.
A DST sponsored project reported high prevalence of the infectious bronchitis virus in Kerala. RT-PCR assays targeting complete S1 subunit of spike gene, N gene and M gene were developed and standardised
Structural and molecular studies on anatomical causes of infertility in crossbred dairy cows of Kerala revealed anoverall incidence estimate of 1.24 per cent. Cervical abnormality was the most common type noticed followed by ovarian hypoplasia, Mullerian duct abnormalities (like aplasia of body of uterus and uterus unicornis) and tubal obstruction. A candidate gene wnt7a that could be used for genome-wide scans of anatomical abnormality in bovine species at early stages itself was identified
Characterization of Retinol Binding Protein 4 (Rbp4) Gene in Malabari and Attappady Black Goats of Kerala revealed monomorphic banding patterns for all six exons, which suggested the highly conserved nature of rBP4 gene in native goat breeds of Kerala
Genetic variability analysis of several differentially expressed genes between different phenotypic groups of poultry and native goat breeds were done and candidate genes that could act as markers for the traits were identified.
Screening of plants for anticancer activity was done and methanol extracts of plants such as Hordeum vulgare, Pergularia daemia Basella alba and Artocarpus hirsutuswere found to have the potential to be used for lead identification.